Weight management is the result of the balance between energy intake and energy consumption. The ingredient DNF-10 promotes weight loss by regulating the mediators of satiety, as various clinical studies prove.
What is DNF-10?
DNF-10 is a food-based ingredient obtained from a screening of low molecular weight peptides after proteolysis of saccharomyces cerevisiae. Saccharomyces cerevisiae (beer yeast, also known as baker’s yeast, brewer’s yeast or wine yeast) is the most commonly used yeast. The yeast is used for fermenting carbohydrates. Studies prove that DNF-10 improves the feeling of satiety and reduces food intake.
The main results of the double-blind, randomized and placebo-controlled clinical trials with a total of 134 subjects:
- Significant reduction in calorie intake from the first week.
- Considerable weight loss after the first month.
- Weight loss due to fat mass.
- Abdominal fat considerably reduced.
- Waist circumference reduced by 5 cm.
After taking DNF-10 for two months, 80% of the subjects thought less of food during the day than at the start of the supplement. The subjects also reduced their calorie intake by 600 calories a day after two months.
DNF-10 and ghrelin
Saturation and appetite are caused by modulation of our levels of ghrelin. A few hours after the last meal there is a slight feeling of hunger. When the stomach empties, it releases ghrelin, the hunger hormone, which functions as a neuropeptide in the central nervous system and initiates the next food intake. Food intake leads to stomach expansion that inhibits the release of ghrelin. DNF-10 acts as a satiety agent in that it reduces the production of ghrelin.